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Chronic Fatigue Syndrome: Beyond the Tiredness Medical Recognition Timeline: 1930: Early outbreaks resembling ME/CFS were documented, such as in Los Angeles (1934) and London (1955, Royal Free Hospital outbreak). These were often labeled as “benign myalgic encephalomyelitis,” implying a post-viral neurological syndrome. 1980s: A cluster of cases in Incline Village, Nevada, drew media and medical attention. It was initially thought to be related to Epstein-Barr virus (EBV), and this led to the term "Chronic Fatigue Syndrome" being coined by the CDC in 1988 to describe the condition. In 1988, the U.S. Centers for Disease Control and Prevention (CDC) introduced the term chronic fatigue syndrome (CFS) to describe a condition characterized by persistent, unexplained fatigue . This terminology was adopted to provide a more neutral and inclusive name, noting that “myalgic encephalomyelitis” was the name most accepted in other parts of the world. Treatment Overview Chronic fatigue ...